Role of HipA and HipB in Bacterial Multidrug Tolerance
During exponential growth of Escherichia coli, one cell per ~1,000,000 becomes dormant. Dormancycan lead to multidrug tolerance, as many antibiotics work by attacking the machinery associated with cell...
View ArticleHydrogen-Stimulated Carbon Catabolism in Enteric Pathogens
H2-oxidizing nickel-containing hydrogenases allow enteric and other pathogens to use H2 within host tissues, and aids pathogens survival within macrophages.Among the genes up-expressed by exposure of...
View ArticleA Novel “Persister” Phenotype of Vibrio Cholerae
Cholera continues to be a major public health threat, particularly in countries where safe drinking water, sanitation and hygiene are suboptimal. Toxigenic Vibrio cholerae, responsible for epidemic...
View ArticleEngineered Bacteria for Efficient Vaccines
Research recently done on genetically engineered strains of bacteria at University of Texas has shown promise to come up with vaccines with improved efficacy. These strains serve as biological...
View ArticleSleeping Sickness more Fatal than Predicted
According to a recent research, Human African trypanosomiasis , the sleeping sickness has a much severe effect on humans than earlier predicted. Sleeping sickness which a parasitic disease usually...
View ArticleEngineered Bacteria can be used as Vaccines
Researchers at the Imperial College London have engineered Salmonella bacteria to use it for vaccination. Normally, Salmonella bacteria possess nanoscopic needles through which it injects its own...
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